Pseudomonas aeruginosa MucD regulates alginate pathway through activation
نویسندگان
چکیده
* Corresponding author 18 Mailing address: Robert C. Byrd Biotechnology Science Center, 1 John Marshall Drive, 19 Huntington, WV 25755-9320; Tel: 304-696-7356; Fax: 304-696-7207 20 E-mail: [email protected] 21 Copyright © 2010, American Society for Microbiology and/or the Listed Authors/Institutions. All Rights Reserved. J. Bacteriol. doi:10.1128/JB.01132-10 JB Accepts, published online ahead of print on 29 October 2010
منابع مشابه
Pseudomonas aeruginosa MucD regulates the alginate pathway through activation of MucA degradation via MucP proteolytic activity.
Alginate overproduction in Pseudomonas aeruginosa can be caused by the proteolysis of the anti-sigma factor MucA regulated by the AlgW protease. Here, we show that inactivation of MucD, an HtrA/DegP homolog and alginate regulator, can bypass AlgW, leading to an atypical proteolysis of MucA that is dependent on the MucP protease.
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